R C Wek Selected Research

Eukaryotic Initiation Factor-2 (EIF 2)

2/2006	Coping with stress: eIF2 kinases and translational control.
7/2001	Mechanism of activation of the double-stranded-RNA-dependent protein kinase, PKR: role of dimerization and cellular localization in the stimulation of PKR phosphorylation of eukaryotic initiation factor-2 (eIF2).
2/2001	Inhibitory sequences in the N-terminus of the double-stranded-RNA-dependent protein kinase, PKR, are important for regulating phosphorylation of eukaryotic initiation factor 2alpha (eIF2alpha).
4/2000	Glucose limitation induces GCN4 translation by activation of Gcn2 protein kinase.
2/2000	A mammalian homologue of GCN2 protein kinase important for translational control by phosphorylation of eukaryotic initiation factor-2alpha.

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R C Wek Research Topics

Disease

3	Starvation 01/2001 - 02/2000
2	Virus Diseases (Viral Diseases) 07/2001 - 02/2001
1	Malnutrition (Nutritional Deficiencies) 02/2006

Drug/Important Bio-Agent (IBA)

5	Eukaryotic Initiation Factor-2 (EIF 2)IBA 02/2006 - 02/2000
4	eIF-2 Kinase (eIF 2 Kinase)IBA 02/2006 - 02/2000
2	Amino Acids FDA Link 04/2000 - 02/2000
1	Insulin (Novolin)FDA Link 02/2006
1	Phosphotransferases (Kinase)IBA 02/2006
1	InterferonsIBA 02/2001
1	Double-Stranded RNA (RNA, Double Stranded)IBA 01/2001
1	CalciumIBA 01/2001
1	Essential Amino AcidsIBA 01/2001
1	A-factor (Streptomyces)IBA 04/2000
1	CarbohydratesIBA 04/2000
1	Glucose (Dextrose)FDA LinkGeneric 04/2000
1	Protein Kinases (Protein Kinase)IBA 04/2000
1	GlycogenIBA 04/2000